Gliclazide can improve muscle strength and recovery in healthy people, but it can also cause weight gain.
Muscle gain
A randomized controlled trial found that taking gliclazide 8 hours before strength training improved exercise performance and muscle recovery.
Gliclazide can stimulate glucose uptake in skeletal muscle by increasing the movement of GLUT4 to the plasma membrane.

Gliclazide also improved muscle recovery 24–48 hours after exercise

Gliclazide can improve blood glucose and glycosylated hemoglobin levels
Gliclazide can reduce platelet adhesion, aggregation, and hyperactivity
Gliclazide can increase fibrinolysis




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