Metformin

11 posts · started by laseruk2507 · Apr 9, 2025

👤
laseruk2507
Junior Member
Posts: 18
Joined: Mar 2025
Rep: 10
👤
laseruk2507
18 posts · joined Mar 2025
#1
I have been reading and reading and reading to learn as much as possible, as I said before I am planning the use HGH at some pint in the future.

I came across the topic of metformin as a replacement to slin. Has anyone heard of this?

I thought I had things pinned down basically, with lantus or long acting slin making things rather simpler, but don;t know how metformin fits into it all?

I'm sure I am over thinking it.
BIGDADDY
MTS STAFF - formally MR BIG
Posts: 2,529
Joined: Jan 2015
Rep: 37
BIGDADDY
2,529 posts · joined Jan 2015
#2
Metformin is not a direct replacement for insulin. They serve very different purposes, even though both relate to glucose metabolism and insulin sensitivity.


When people use HGH, especially in higher doses, it can cause insulin resistance over time. That’s where metformin can come into play, it helps improve insulin sensitivity and reduces glucose production in the liver. In that sense, it helps mitigate some of the negative effects of HGH on blood sugar levels and insulin response.


Insulin, especially long-acting like Lantus or fast-acting post-workout slin, is used for its anabolic effect. It helps shuttle nutrients, especially glucose and amino acids into the muscle cells, boosting recovery and growth.

When combined with HGH, it can create a very powerful environment for muscle gain. That’s why a lot of advanced users pair HGH with insulin rather than metformin.


Metformin, on the other hand, doesn’t spike insulin. It doesn’t have any anabolic properties on its own. It’s more about keeping things under control if you’re trying to stay lean or avoid the insulin resistance that can come with long-term HGH use.


Some people use metformin alongside low-dose HGH during cutting phases or even in health-focused protocols. Others might use it in combination with insulin to help balance the effect, for example, using Lantus in the morning and metformin at night.


So to answer your question, metforminwon’t replace insulin if your goal is to maximize anabolic growth from HGH. It can be a support compound, especially if you want to avoid insulin for now or are concerned about insulin resistance.
MTS Support https://support.med-tech.pro
👤
laseruk2507
Junior Member
Posts: 18
Joined: Mar 2025
Rep: 10
👤
laseruk2507
18 posts · joined Mar 2025
#3
Thanks for taking the time to answer so throughly, this really helps give me a clearer picture of it all.

I'm still a while away from trying HGH, maybe say 6 months away, but I will keep learning.

I always like to have things sorted out in my head before I try something new.
👤
DarrenW29
Senior Member
Posts: 1,651
Joined: Apr 2020
Rep: 89
👤
DarrenW29
1,651 posts · joined Apr 2020
#4
Long acting or gliclazide

If insulin resistance is present due to hgh usage

But first check blood sugar fasted then 2 hours after eating then last hba1c blood test to check 3 month of blood sugars
👤
laseruk2507
Junior Member
Posts: 18
Joined: Mar 2025
Rep: 10
👤
laseruk2507
18 posts · joined Mar 2025
#5
Do you use a CGM monitor or just finger prick with a normal tester each time you need to measure?

Long acting slin would seem easier to manage I suppose, but short acting you would have to eat 15mins after, around 10cards per iu I have read?
👤
DarrenW29
Senior Member
Posts: 1,651
Joined: Apr 2020
Rep: 89
👤
DarrenW29
1,651 posts · joined Apr 2020
#6
Correct on fast acting mate
Long acting way easier to use
25-30iu upon waken

Finger prick blood sugar monitor

Always carry sugar on you still just incase
👤
laseruk2507
Junior Member
Posts: 18
Joined: Mar 2025
Rep: 10
👤
laseruk2507
18 posts · joined Mar 2025
#7
Thanks Darren.

Intra workout if using fast slin before workout would that be a dextrose shake or something? I imagine anything else would make you feel sick?
👤
DarrenW29
Senior Member
Posts: 1,651
Joined: Apr 2020
Rep: 89
👤
DarrenW29
1,651 posts · joined Apr 2020
#8
I hate insulin pre workout if anything post workout dextrose jams dextrin bud yeah
👤
laseruk2507
Junior Member
Posts: 18
Joined: Mar 2025
Rep: 10
👤
laseruk2507
18 posts · joined Mar 2025
#9
Thanks. Your log is great btw, insane size bro.
👤
DarrenW29
Senior Member
Posts: 1,651
Joined: Apr 2020
Rep: 89
👤
DarrenW29
1,651 posts · joined Apr 2020
#10
Thank you mate 🙏
👤
laseruk2507
Junior Member
Posts: 18
Joined: Mar 2025
Rep: 10
👤
laseruk2507
18 posts · joined Mar 2025
#11
Would cyclic dextrin be ok as carbs after using a fast acting slin?

Also just trying to figure out, since lantus is slow acting, how do you adjust your food intake during the day? Since most bodybuilders are eating larger amounts is it something not to worry about?

Thanks!
Reply

📦 Move Thread

✂️ Split Thread Here

This post and all following posts will become a new thread.