DarrenW29
05-08-2021, 01:12 PM
I didn’t write this but a interesting upload.
To first understand why you are doing what you are doing I am going to go over a few things and a few definitions:
selective estrogen receptor modulator ? Selective estrogen receptor modulator. These drugs work by binding to the estrogen receptors and flooding them in a sense, making it difficult (but not impossible by any means) for estrogen to bind to the receptors and thus prevent the onset of estrogen related side effects.
Most common forms: Tamoxifen (Nolvadex), Clomiphene (Clomid)
aromatase inhibitor ? Aromatise Inhibitor. These drugs work by inhibiting the aromatization of estrogen. This means that in effect aromatase inhibitor?s prevent androgens from converting to estrogen, again, making it difficult (but not impossible) for estrogen to reach receptor sites.
Most common forms: Anastrozole (l-dex, a-dex), Exemestane (aromasin), Femera (letrozole). For our purpose of reversing gynecomastia we are interested in letro.
letro and your sex drive:
Letrozole will suppress your sex drive. This is another reason why it is so important to act on preventing gynecomastia as soon as possible. Since we all know that Test should be run in every cycle this will cancel out the effect of sex drive suppression.
Running letro to prevent gynecomastia:
If you decide to run estrogen protection while on cycle (and I suggest you do unless you are aware that you do not require it), you can run either a selective estrogen receptor modulator or an aromatase inhibitor. letro will be the most powerful aromatase inhibitor you can use, it will inhibit 98+% of estrogen using a dose as low as .25mg and even lower. This is why I suggest you do not use a dose higher than .50mg while on cycle just trying to prevent estrogen related side effects.
You will want to start running the letro approximately 2 weeks before you begin your cycle to allow it to fully stabilize in your blood. I have often heard the argument that letro takes up to 60 days to stabilize, I don?t know if I buy into this for the reason that I have reversed gynecomastia after using letro for only 1 week. Still to be safe I recommend starting it before your cycle as stated above.
If you do decide to run letro there is absolutely no need to run another aromatase inhibitor or selective estrogen receptor modulator. Do not make the mistake of thinking more is better. Think of it this way; if letro is preventing the conversion of androgens to estrogen than there is no estrogen, what would the purpose of a selective estrogen receptor modulator be when there is no estrogen to bind to the receptors? nolva will only take away from the effectiveness of letro.
This brings me to my next point. Do not listen to anyone who tells you to bump up your nolvadex to 60+mg ED if you get gynecomastia. I have no idea where this idea started but I have seen it suggest far too many times recently. Nolvadex will do nothing to reverse your gynecomastia?let me make that clear IT WILL DO NOTHING FOR gynecomastia. If you are running nolva as your Anti-E and start to develop gynecomastia than sure you can bump the dosage a small amount to try to prevent it from progressing further, but letrozole must begin ASAP.
It is very important that you begin taking letrozole immediately, the longer your wait the more risk you take in not being able to reverse it.
How do I know if I have gynecomastia?
If you have developed gynecomastia you will have a lump behind your nipple. It will be fairly hard, and it will be tender to touch.
Running letro to reverse gynecomastia:
I am going to go over the three different scenarios which people could fit into. Remember regardless of what scenario you are in it is important that you begin taking the letro ASAP.
1. Already using an Anti-E aside from letro.
2. Already using letro @ a dose of .25mg or .50mg ED.
3. Not running any estrogen protection.
1.
Day 1: .25mg letro + Anti-E*
Day 2: .50mg letro
Day 3: 1.0mg letro
Day 4: 1.5mg letro
Day 5: 2.0mg letro
Day 6: 2.5mg letro **
2.
Day 1: .50mg letro
Day 2: 1.0mg letro
Day 3: 1.5mg letro
Day 4: 2.0mg letro
Day 5: 2.5mg letro **
3.
Day 1: .50mg letro
Day 2: 1.0mg letro
Day 3: 1.5mg letro
Day 4: 2.0mg letro
Day 5: 2.5mg letro **
*Regardless of the Anti-E you are using it is important to still use it for the first day you begin letro as the letro will not have taken any effect and you by no means want your body to be without any protection when gynecomastia is already prevalent.
** You will remain at this dose until gynecomastia symptoms subside. Once you believe your gynecomastia is gone it is important to stay at this dose for another 4-7 days to ensure all traces are gone. I recommend people with a bf% over 15 stay on for a week as it may be harder to judge completely whether the lump is completely gone. Once this period is over it will be important to taper letro down slowly rather than coming off it completely. Regardless of which manner you tapered up your dose you will all taper down in the same fashion.
Day 1: 2.0mg
Day 2: 1.5mg
Day 3: 1.0mg
Day 4: .50mg***
Day 5: .25mg
***You can remain at this dose or go down further to .25mg. It is really up to you at this point. They are both very common maintenance doses as an Anti-E while on cycle. Personally I have sta with .25mg and never had a problem.
letro and the estrogen rebound:
With your estrogen being completely inhibited there is a definite estrogen rebound as your body tries to re-stabilize the testosterone:estrogen balance. We can prevent this rebound effect by supplementing further with another aromatase inhibitor or selective estrogen receptor modulator aka nolvadex
Dont mistake bodyfat for gyno
To first understand why you are doing what you are doing I am going to go over a few things and a few definitions:
selective estrogen receptor modulator ? Selective estrogen receptor modulator. These drugs work by binding to the estrogen receptors and flooding them in a sense, making it difficult (but not impossible by any means) for estrogen to bind to the receptors and thus prevent the onset of estrogen related side effects.
Most common forms: Tamoxifen (Nolvadex), Clomiphene (Clomid)
aromatase inhibitor ? Aromatise Inhibitor. These drugs work by inhibiting the aromatization of estrogen. This means that in effect aromatase inhibitor?s prevent androgens from converting to estrogen, again, making it difficult (but not impossible) for estrogen to reach receptor sites.
Most common forms: Anastrozole (l-dex, a-dex), Exemestane (aromasin), Femera (letrozole). For our purpose of reversing gynecomastia we are interested in letro.
letro and your sex drive:
Letrozole will suppress your sex drive. This is another reason why it is so important to act on preventing gynecomastia as soon as possible. Since we all know that Test should be run in every cycle this will cancel out the effect of sex drive suppression.
Running letro to prevent gynecomastia:
If you decide to run estrogen protection while on cycle (and I suggest you do unless you are aware that you do not require it), you can run either a selective estrogen receptor modulator or an aromatase inhibitor. letro will be the most powerful aromatase inhibitor you can use, it will inhibit 98+% of estrogen using a dose as low as .25mg and even lower. This is why I suggest you do not use a dose higher than .50mg while on cycle just trying to prevent estrogen related side effects.
You will want to start running the letro approximately 2 weeks before you begin your cycle to allow it to fully stabilize in your blood. I have often heard the argument that letro takes up to 60 days to stabilize, I don?t know if I buy into this for the reason that I have reversed gynecomastia after using letro for only 1 week. Still to be safe I recommend starting it before your cycle as stated above.
If you do decide to run letro there is absolutely no need to run another aromatase inhibitor or selective estrogen receptor modulator. Do not make the mistake of thinking more is better. Think of it this way; if letro is preventing the conversion of androgens to estrogen than there is no estrogen, what would the purpose of a selective estrogen receptor modulator be when there is no estrogen to bind to the receptors? nolva will only take away from the effectiveness of letro.
This brings me to my next point. Do not listen to anyone who tells you to bump up your nolvadex to 60+mg ED if you get gynecomastia. I have no idea where this idea started but I have seen it suggest far too many times recently. Nolvadex will do nothing to reverse your gynecomastia?let me make that clear IT WILL DO NOTHING FOR gynecomastia. If you are running nolva as your Anti-E and start to develop gynecomastia than sure you can bump the dosage a small amount to try to prevent it from progressing further, but letrozole must begin ASAP.
It is very important that you begin taking letrozole immediately, the longer your wait the more risk you take in not being able to reverse it.
How do I know if I have gynecomastia?
If you have developed gynecomastia you will have a lump behind your nipple. It will be fairly hard, and it will be tender to touch.
Running letro to reverse gynecomastia:
I am going to go over the three different scenarios which people could fit into. Remember regardless of what scenario you are in it is important that you begin taking the letro ASAP.
1. Already using an Anti-E aside from letro.
2. Already using letro @ a dose of .25mg or .50mg ED.
3. Not running any estrogen protection.
1.
Day 1: .25mg letro + Anti-E*
Day 2: .50mg letro
Day 3: 1.0mg letro
Day 4: 1.5mg letro
Day 5: 2.0mg letro
Day 6: 2.5mg letro **
2.
Day 1: .50mg letro
Day 2: 1.0mg letro
Day 3: 1.5mg letro
Day 4: 2.0mg letro
Day 5: 2.5mg letro **
3.
Day 1: .50mg letro
Day 2: 1.0mg letro
Day 3: 1.5mg letro
Day 4: 2.0mg letro
Day 5: 2.5mg letro **
*Regardless of the Anti-E you are using it is important to still use it for the first day you begin letro as the letro will not have taken any effect and you by no means want your body to be without any protection when gynecomastia is already prevalent.
** You will remain at this dose until gynecomastia symptoms subside. Once you believe your gynecomastia is gone it is important to stay at this dose for another 4-7 days to ensure all traces are gone. I recommend people with a bf% over 15 stay on for a week as it may be harder to judge completely whether the lump is completely gone. Once this period is over it will be important to taper letro down slowly rather than coming off it completely. Regardless of which manner you tapered up your dose you will all taper down in the same fashion.
Day 1: 2.0mg
Day 2: 1.5mg
Day 3: 1.0mg
Day 4: .50mg***
Day 5: .25mg
***You can remain at this dose or go down further to .25mg. It is really up to you at this point. They are both very common maintenance doses as an Anti-E while on cycle. Personally I have sta with .25mg and never had a problem.
letro and the estrogen rebound:
With your estrogen being completely inhibited there is a definite estrogen rebound as your body tries to re-stabilize the testosterone:estrogen balance. We can prevent this rebound effect by supplementing further with another aromatase inhibitor or selective estrogen receptor modulator aka nolvadex
Dont mistake bodyfat for gyno