First proper blast at 500mg after 22 months on TRT cruise, what actually changes and when?

[BERLINER]

I have been on 200mg TRT for 22 months. Starting a proper blast at 500mg test e this month. I understand the additional 300mg is not a large jump from a hormonal standpoint but I expect the anabolic environment to be meaningfully different. My baseline bloods are documented from the TRT period. I will be tracking E2 closely as my AI requirement will change at blast dose. Who has made this specific transition from established TRT to first blast and what changed most noticeably?