sitagliptin Gain muscle loose fat
Januvia (sitagliptin) may increase muscle mass and the ratio of muscle to fat in people with type 2 diabetes. However, weight gain is not a common side effect of Januvia.
How Januvia affects muscle
A 2020 study found that sitagliptin increased muscle mass and the ratio of muscle to fat in patients with type 2 diabetes.
Sitagliptin increases the expression of PGC1β in skeletal muscle, which may improve glucose metabolism and insulin resistance.
Sitagliptin may also increase the expression of FNDC5, which may increase the expression of PGC-1α in skeletal muscle cells.
It's seems that Januvia (and all the DPP-4I) work by reducing DPP-4 activity on the cell membrane and bloodstream, the result is that all growth factors and incretine hormones will have an extended activity life.
Basically IGF1, Insulin, IGF2, EPO, Chemokines, Neuropeptides, Vasoactive Peptides will work "better" and for more time.
50-100mg Januvia ed should give a nice boost to our cycles when using HGH and Insulin (and IGF1-LR3), with less.we can have more result.
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