Mirabegron fat loss and improving insulin sensitivity

[DarrenW29]

Mirabegron helps fat loss targeting the beta 3 increasing resting metabolic rate and inducing brown fat activity

it also increases insulin sensitivity in muscle tissue

dosages of
100-200mg per day

downside
hard to get
not cheap
doctors won’t prescribe it.


Mirabegron is a β3-agonist drug approved by the FDA for use in 2012 and administered in overactive bladder. Activating of adrenergic receptors leads to the relaxation of the detrusor muscle. According to the latest research and reports, it also has lipolytic activity, affecting the reduction of mainly brown adipose tissue (BAT) but also of white adipose tissue (WAT). This results in a decrease in body weight and triglyceride concentration and an increase in lipoprotein lipase activity, as well as in the level of free fatty acids or adipokines in the plasma. The drug indirectly participates in the regulation of carbohydrate metabolism, influencing the increase in insulin sensitivity, supporting cellular uptake of glucose.

Keywords: Mirabegron; drug; exercise; insulin sensitivity; lipolysis; β3-agonist.



study
https://physoc.onlinelibrary.wiley.c...814/phy2.14779