ill try find it for you tommo, unlikely im confused but maybe. i remember reading it somewhere.Originally Posted by brimmy
ill try find it for you tommo, unlikely im confused but maybe. i remember reading it somewhere.
ok i cant sleep so here it goes
http://www.ncbi.nlm.nih.gov/pubmed/22906881
see also
Llewellyn W. Dianabol (methandrostenolone). Anabolics 2005. Body of Science Press, Jupiter, FL;2005:114-8.
Llewellyn W. Deca-durabolin (nandrolone decanoate). Anabolics 2005. Body of Science Press, Jupiter, FL;2005:109-12.
Babigian A, Silverman RT. Management of gynecomastia due to use of anabolic steroids in bodybuilders. Plast Reconstr Surg, 2001;107:240-2.
Markiewicz L, Gurpide E. Estrogenic and progestagenic activities of physiologic and synthetic androgens, as measured by in vitro bioassays. Methods Find Exp Clin Pharmacol, 1997;19:215-22.
Walton MJ, Kumar N, et al. 7alpha-methyl-19-nortestosterone (MENT) vs testosterone in combination with etonogestrel implants for spermatogenic suppression in healthy men. J Androl, 2007;28:679-88.
Auvray P, Nativelle C, et al. Study of substr,ate specificity of human aromatase by site directed mutagenesis. Eur J Biochem, 2002;269:1393-1405.
Reznik Y, Dehennin L, et al. Urinary nandrolone metabolites of endogenous origin in man: a confirmation by output regulation under human chorionic gonadotropin stimulation. J Clin Endocrinol Metab, 2001;86:146-50.
Hobbs CJ, Jones RE, et al. Nandrolone, a 19-nortestosterone, enhances insulin-independent glucose uptake in normal men. J Clin Endocrinol Metab, 1996;81:1582-5.
Dintinger T, Gaillard JL, et al. Androgen and 19-norandrogen aromatization by equine and human placental microsomes. J Steroid Biochem, 1989 Nov;33(5):949-54.
Moslemi S, Auvray P, et al. Structure-function relationships for equine and human aromatases. A comparative study. Ann NY Acad Sci, 1998;839:576-7.
Simpson ER, Davis SR. Minireview: aromatase and the regulation of estrogen biosynthesis— some new perspectives. Endocrinology, 2001;142(11):4589-94.
Gaillard JL, Silberzahn P. Aromatization of 19-norandrogens by equine testicular microsomes. J Biol Chem, 1987 Apr 25;262(12):5717-22.
Roselli CE. The effect of anabolic-androgenic steroids on aromatase activity and androgen receptor binding in the rat preoptic area. Brain Res, 1998 May 11;792(2):271-6.
Kuhl H, Wiegratz I. Can 19-nortestosterone derivatives be aromatized in the liver of adult humans? Are there clinical implications? Climacteric, 2007;10:344-53.
but it makes sense, ppl hold water on test..ppl hold more water on test + deca..but deca solo is little water like eq
Very interesting, Magician! I knew Nandrolone upregulates Aromatase but I never knew it was by as much as 40% increase in rate of aromatisation!! Crazy!
I'm dropping deca now, replaced it with tri bold
As for OP, it really could be estrogen. I have never had issues with deca dick and I have blasted deca as high as gram with 300 test no AI no problems with penis.
My friends have run deca solo, no issues either with sex drive or penis
U mentioned that u used letro
I can say 100% that too low estrogen makes your dick not respond no any sexual stimulation, maybe u lwoered it too much
do you have any low estro symptoms? it could be not problem from deca but from estrogen (too low or too high)
i think i was mistaken about the 40% , i think i got confused with test aromatising upwards of 40%Very interesting, Magician! I knew Nandrolone upregulates Aromatase but I never knew it was by as much as 40% increase in rate of aromatisation!! Crazy!
I'm dropping deca now, replaced it with tri bold
As for OP, it really could be estrogen. I have never had issues with deca dick and I have blasted deca as high as gram with 300 test no AI no problems with penis.
My friends have run deca solo, no issues either with sex drive or penis
but deca defs increases it im not sure on the number though
too many things bad about letro
I would drop it and use calcium d glucirate itll give you normal estrogen balance,
"Also ever took letro and still had nipple sentivity? Wonder why? Letro lowers shgb dramatically this allows free testosterone to spike and as a result free estrogen, this is the reason the letro gyno reversal protocol doesn?t work"
you meant calcium d glucarate.
What ?
I'm suggesting he try calcium d glucirate over the letro, costs like 20$ ..
drop test and use more deca. keep estro in check and you wont have prolactin issues. test is the problem maker
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