What is IGF1-LR3 and a personal review

IGF-1 LR3IGF-1 is a peptide roughly the same structure and size as insulin, or about 70 amino acids long. It belongs to the peptide family of substances identified as growth factors. It is a highly anabolic hormone released in the liver as well as in peripheral tissues such as skeletal muscle. In the body, IGF-1 is released in response to the presence of Human Growth Hormone (HGH). After intense resistance training, the body experiences a surge in GH and IGF, and this is one way that new muscle is built. Although GH is considered to be highly anabolic, in actuality, IGF-1 is suspected to be responsible for the primary anabolic activities of GH.

IGF-1 builds new muscle tissue by promoting nitrogen retention and protein synthesis. This causes the growth of muscles through both hyperplasia (which is an increase in number of muscle cells) and mitogenesis (which is the actual growth of new muscle fibers). Thus IGF-1 not only makes muscle fibers bigger, it makes more of them as well!

IGF-1’s effects are not limited to building new muscle, however. It has a potent effect on lipid (fat) metabolism, and helps the body burn fat at a significantly elevated rate. In addition, IGF-1 is both a neuroprotector and neuropromotor, which improves mental functions such as reflexes, memory, and learning ability. IGF is also important for production of connective tissue andIGF-1 insuring proper bone density.

Although IGF-1 is very potent at building muscle and burning fat, the Lr3 IGF-1 version is roughly 2-3x as powerful.

Lr3IGF-1 (Long R3 Insulin-like Growth Factor-I or Long R3IGF-I) is an 83 amino acid analog of human IGF-I actually comprising the complete human IGF-1 sequence but with the substitution of an Arg for the Glu at position 3, as well as a 13 amino acid extension peptide at the N-terminus. This makes Long R3IGF-I significantly more potent (2-3x) than IGF-I in studies, because it has a lower affinity to be rendered inactive by IGF binding proteins, and consequently more potential activity in the body.

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I will give my review:

I have used IGF1-LR3 on 100mcg dosage 5x a week (pre-workout), i feel a good pump, like a powerful oral (something like dianabol), and then i increased the dose to 200mcg 5x a week (post-workout) and i feeeel very better, good pumps and thinning of the skin (not like GH or Increlex LOL) but veins on forearms and a full aspect on the shoulder
I was using 700mg NPP and 225mg of Test

My opnion? Go to high dosages, like 500-750mcg on workout days, and i dont believe on saturation, i have used for 5 weeks only on workout days and i feel very better. And have carbs with IGF1LR3, you will feel the hypo effect

Oh yea, i made two reconstructions

A vial only with sterile water and another with bacteriostatic water, i didnt feel any difference, but i read on some place that bacteriostatic water will preserve the IGF1LR3 more

Quote:

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Originally Posted by 41154135

My opnion? Go to high dosages, like 500-750mcg on workout days, and i dont believe on saturation, i have used for 5 weeks only on workout days and i feel very better. And have carbs with IGF1LR3, you will feel the hypo effect

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I used IGF1 LR3 from a good source in China. Since I was a long standing customer, he offered money back guarantees on his IGF1-LR3. I followed what you said... and exactly what you said. I was so dumb to take Humalog with it... I had to drink nearly 1 litre of pineapple juice, a box of tim-tams, 3 bananas, 2 bags of skittles and 2 bowls of ice cream to STOP the hypo effect.

When I tried with another brand (won't name brands - as not to appear bias or discredit any particular brand), with Humalog like before... NOTHING.... garbage.

I have used some american brand and chinese brand, i didnt feel nothing with chinese brand, with the american even on low dosage i feel a little hypo
IGF2-LR3 seems to be very powerful, but its rare to find.

I have used IGF1-lr3..500 mcg a day in a 300 defecit

americian brand.. Cost me a.lot lol

Pumps were just godly. I'd do like 12 reps ohp and have to stop in pain.. id hobble back to a bench or something to ait on with a full bosy pump... Ahkulders a mass of red full thin akinned veins

Lost a shit load of bf

Was red full veiny etc all thr time

Wht is the difference between Increlex and lr3? I thought increlex was just fda approved lr3?

Quote:

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Originally Posted by Powertard

I have used IGF1-lr3..500 mcg a day in a 300 defecit

americian brand.. Cost me a.lot lol

Pumps were just godly. I'd do like 12 reps ohp and have to stop in pain.. id hobble back to a bench or something to ait on with a full bosy pump... Ahkulders a mass of red full thin akinned veins

Lost a shit load of bf

Was red full veiny etc all thr time

Wht is the difference between Increlex and lr3? I thought increlex was just fda approved lr3?

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nope, IGF1LR3 is just a GDA (Glucose Disposal Agent) like a insulin without sides, igf1lr3 can't bind to BP3 like rHIGF1 (Increlex or Iplex - a blend of IGF1 and IGFBP3), so you need a raise of systematic IGF1 and IGF2, not a effect of GDA (hypoglicemic) of IGF1, you need everything... Thin skin, blow up muscle, etc.

IGF1LR3 is very good on high doses.

And on my opnion of course, a blend of IGF1LR3 and IGF2LR3 should be good LOL, at 500mcg each, i would imagine the freakness, not like increlex, but should be good

Quote:

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Originally Posted by Powertard

I have used IGF1-lr3..500 mcg a day in a 300 defecit

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Hi all,

I used chinese IGF 1 -lr3 last, 2 years ago. Pumps were godly also.

I just received some last week, and mixed up a 1000mcg vial yesty.

It has been so long since my peptides that I have gotten the dosages wrong.. and i'm starting to freak out. I have nearly had half a vial in just 1 day...

went to gym this morning after second shot, and there is nothing in the way of super pumps. but definitely feel a bit fuller.

no real hunger yet, but im trying to east as much as possible, becasue i remember how bad the hypo was last time.

my concern is the dosage that I have had, but after googling a HEAP, I see that you said that you have ran 500mcg before, you mean you do 10 times the norm (like i accidentally have?) reguarly??? on purpose? isn't 50mcg the norm? thats what I did last time.

should i be concerned, or what now?

Just checked. 3/4s of a vial in just 24 hours.

oh my goodness!!!!!

24 hours later.

NEARLY DIED!

My advice, do NOT do what I did!!!

still feel shaky from it

How do you know you nearly died?

few days on and i still have anxiety, and hunger feelings... way too much I had.

i was just sitting at my desk, when all of a sudden, i lost my mind, and panicked.. felt like a hash cookie or something.

high blood pressure. 130bpms... just freaking, hypo is some scary stuff.

While unpleasent that doesn't mean you nearly died lol

You said your blood sugar was 6 in a PM to me which is healthy range right?

yes, healthy range... maybe it was just anxiety...

Most probably some physiologic reaction but I don't think you died, I think you had a panic attack

do you do micro IM injections at site, or SQ/IM inject full dose?

Quote:

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Originally Posted by littlealan

24 hours later.

NEARLY DIED!

My advice, do NOT do what I did!!!

still feel shaky from it

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You have to know about you bodybuilding. I have trained fasted using 100mcg of IGF1LR3 (6-8 hours fasted and i just injected and go to workout). On 200mcg of IGF1LR3 i feel like im using 5-7ui of insulin, like i said before IGF1LR3 IS A GDA LIKE INSULIN! YOU HAVE CARBS ON YOUR HANDS TO USE A HIGH DOSE LIKE 500-750MCG...... Let me write: HAVE CARBS TO USE IGF1LR3 HAVE CARBS TO USE IGF1LR3 HAVE CARBS TO USE IGF1LR3 HAVE CARBS TO USE IGF1LR3 HAVE CARBS TO USE IGF1LR3

IGF1LR3 can be inject IM or SQ, i prefer IM.

I was thinking to use 100mcg daily - when it s best to take? I was thinking post workout but I'm on low Carb diet now

Quote:

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Originally Posted by kafka82

I was thinking to use 100mcg daily - when it s best to take? I was thinking post workout but I'm on low Carb diet now

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http://www.musclechemistry.com/uploa...igf-1-lr3.html

What is the best way to use it in your opinion?

"The best way to use it is to use it in regulated dosages. Ususal dosages of Long R3 IGF-1 are 10mcg to around 50mcg per day. IGF is usually available by the milligram (1000mcg), which is equivalent to using 20mcg a day for 50 days. But for the most part, the actual dosage depends upon how much the person is able to spend on Long R3 IGF-1, although most are usually satisfied with the 20mcg per day dosage. Additionally, IGF is also best taken either IM or subcutaneously, having more direct effects on the body when injected. It's also recommended to be taken during the morning or after weight training sessions."

So the only useful dose is 500mcg before WO? After WO?

I have some IGF1-LR3 from an american brand and tbh i will never buy it from them. Did 100mcgs split on each muscle, but didn't feel any hypo synthomps... maybe i just have to up the dose?