Wife low test/estrogen - early menopause

4 posts · started by squirms · Apr 25, 2026

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squirms
Junior Member
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Joined: Oct 2019
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squirms
25 posts · joined Oct 2019
#1
Hey fellas,
Wife is going through peri-menopause (44 yrs old) has had several tests done, low estrogen relatively low testosterone, too. Have been thinking and discussing with her female trt. Has anyone else's wife/girlfriend/female friend/acquaintance use or using TRT?
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Beantown Rick
Posts: 552
Joined: Jun 2016
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Beantown Rick
552 posts · joined Jun 2016
#2
Yeah, went through this with my wife a couple years ago. Similar age, bloodwork showed low E2 and below-range free test. She's been on a low dose estrogen patch plus a small testosterone pellet every 3 months. Night sweats cleared up, energy and mood noticeably better within about 6 weeks. The key is finding a doctor who actually tests free testosterone for women and not just the standard hormone panel, most GPs miss it completely.
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squirms
Junior Member
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Joined: Oct 2019
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squirms
25 posts · joined Oct 2019
#3
Thanks for sharing pal
I was thinking eventually (blood work etc permitting) using test or, if possible get a more diluted form of testosterone cyp like 20mg or 50mg per ml in order to accurately dose. From what I've read women on TRT are anywhere from 6-15mg per week
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FrankfurtFit
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FrankfurtFit
783 posts · joined Jun 2015
#4
6-15mg/week is the right ballpark for women. Most find their sweet spot around 8-10mg once bloods are dialled in, some need a bit less if they're sensitive to androgen sides at all.

The diluted cyp idea makes a lot of sense. Standard 200mg/ml is a nightmare to dose accurately at those amounts, 20-50mg/ml is much more manageable. Some go the cream or gel route for the same reason, easier to adjust without worrying about tiny volume differences in a syringe.

Just get a baseline on her total test, free test and E2 before starting. Women respond fast to even small doses and you want to know where she is before adding anything.
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