PT-141 for libido, did the shot actually work for you and how bad was the nausea?

2 posts · started by FLbodybuilder · Jul 19, 2026

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FLbodybuilder
Posts: 1,363
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FLbodybuilder
1,363 posts · joined Feb 2015
#1
Been looking at PT-141 for a while. Currently running a solid blast so erections aren't the issue but libido is just flat, which is a different problem. Saw it come up in a few threads and the mechanism makes sense to me, it's hitting desire through the brain rather than just blood flow. That's the distinction I've been missing trying to fix it with cialis alone.

Anyone actually run it? Specifically want to know whether the libido bump was real and noticeable or whether you were left wondering if it did anything. And the nausea, everyone mentions it but how bad was it on 1.5mg, manageable or is ondansetron beforehand basically mandatory?
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FrankfurtFit
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FrankfurtFit
805 posts · joined Jun 2015
#2
The nausea is very real on the first couple tries. Running ondansetron 4mg about 30 minutes before sorted it almost completely for me. The libido hit is genuine though, it is a brain thing not a blood flow thing so it actually does something different than a PDE5. A lot of guys end up stacking both, PT-141 for the desire side and cialis for the mechanics, and that combination is pretty solid. Start at 1mg and see how you react before jumping to the full 1.5, the responses are all over the place person to person.
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