Added Proviron to TRT cruise and dropped my AI completely, sharing the labs

Eight weeks into adding Proviron 25mg daily to 200mg test weekly TRT. Dropped adex at week four, E2 has held at 31 pg/mL on the last two draws. Libido is noticeably better. SHBG went from 44 to 29 nmol/L. Free test calculation improved accordingly. Hair is not visibly worse at 25mg. The mild anti-estrogenic effect at this dose is real and the bloodwork confirms it. Considering going to 50mg but not sure the benefit justifies the DHT load increase for a TRT cruise.

25mg is where I stay mate. Tried 50mg for 8 weeks and the hairline started showing stress. Dropped back to 25mg and the SHBG benefit is still real at that dose. Free test is noticeably higher on labs. The libido improvement takes about 3 weeks to become obvious. No point pushing to 50mg if you care about your hair - 25mg gets you most of the benefit without the DHT load of the higher dose.

I run 50mg daily on TRT cruise and notice a clear difference versus 25mg in terms of drive and mood. No hair issues personally but I'm not predisposed. The SHBG-binding effect is dose-dependent so there is a real difference between the two doses. Hair-sensitive guys should stay at 25mg and not push it. For me the 50mg benefit is worth it given my particular situation.

The mechanism is well established - Proviron binds SHBG with high affinity, displacing testosterone and increasing the free fraction. At 25mg the effect on SHBG is meaningful. At 50mg you get a stronger SHBG suppression plus a mild anti-estrogenic effect via aromatase competition. The difference between the two doses is real but individual SHBG level determines how much of that difference you actually feel. Men with naturally high SHBG will notice the step up to 50mg more than men who run low SHBG.