Caber or prami for prolactin on NPP - is the standard 0.25mg twice a week actually doing anything or are you just guessing?

Caber 0.25mg twice a week. Pulled prolactin at week 6 on NPP 400mg and it came back at 16 ng/ml. Well managed with that dose and no side effects worth mentioning. Never felt the need to try prami.

Prami is brutal. Used it once and never again. Caber 0.25mg twice a week handles prolactin properly and the only side you might get is mild dizziness the first few days. Not comparable to what prami does to you.

Caber every time mate. Prami is a headache I do not need - the vivid dreams and nausea on the one run I did made it a non-starter. 0.25mg twice a week handles any prolactin issue from NPP at sensible doses without the baggage.

Running NPP at 400mg per week alongside test for the first time and reading the standard advice everywhere of caber 0.25mg twice weekly as a default. Ran my prolactin pre-cycle and it was 9 ng/ml. Curious how many of you actually pulled prolactin labs on cycle and saw what the numbers did, or whether you're just running caber prophylactically because the forum says to. The other question is whether anyone here has run pramipexole instead and what the trade-off looked like. I'd rather dial this in based on real numbers than just throw caber at it and hope.

This is exactly the issue with running 19-nors on feel alone. Ran NPP at 400mg for 10 weeks and my prolactin numbers were fine the whole way through without caber. Then ran it again at the same dose 6 months later and hit 45 ng/mL by week 6. Same compound, same dose, totally different response. Now I pull a prolactin alongside my mid-cycle panel every single run regardless of symptoms. The cost of one extra bloodwork marker is nothing compared to the cost of finding out late.

Good discussion. The point about testing rather than assuming is the one worth taking seriously. Some guys run caber for years on every nandrolone cycle and never actually check whether their prolactin is elevated - it may not be, and caber has its own side effect profile at sustained doses. Pull a prolactin panel at week 6 alongside your other mid-cycle bloods and let the number guide the decision.

Tried prami once on a tren run a few years back and went back to caber after 10 days. The vivid dreams were weird enough but I had genuine compulsive behaviour stuff going on that made me uncomfortable. Caber at 0.25mg twice a week handles prolactin fine for most NPP doses and the side effect profile is nowhere close to what prami puts you through. Prami is more potent per mg but that doesn't make it better, just harder to manage.

The prami sides are no joke. Tried it once on a deca run because I couldn't get caber at the time, the vivid dreams were actually manageable but the nausea the first week was rough. Switched back to caber as soon as I could and never looked back. 0.25mg twice a week handles my prolactin on 400mg NPP no problem. Some guys seem to tolerate prami fine but for most people I'd say caber is the easier path.

The point about actually testing prolactin rather than just dosing prophylactically is the key takeaway here. Some guys never need caber on NPP, others spike hard at 300mg. Running it blind without numbers is just guessing.

The two symptoms that show up before any nipple issues are libido going flat and difficulty finishing. Most guys blame E2 or just being run down on cycle, so it gets written off for weeks. If both are there together while running NPP, prolactin should be the first thing you pull. Wait until week 6 minimum though. Levels are still building at week 2-3 and you'll pull it thinking you're fine when you're not.

Good thread. One thing worth adding - if you are running NPP and your libido drops noticeably before any nipple sensitivity appears, run a prolactin test before adjusting the caber dose. Low libido is often the first symptom and it is easy to misread as an E2 issue and end up chasing the wrong number.

Tried prami once and the dream side was something else. Not just vivid, like full cinema-level stuff every single night. Switched back to caber after 2 weeks. The compulsive behaviour thing is real too, I noticed I was being impulsive about dumb stuff that I'd normally not think twice about. Caber at 0.25mg twice a week handles my prolactin fine on NPP - I've confirmed it via bloods at week 6 so it's not just guesswork. If your numbers aren't spiking at that dose there's genuinely no reason to even look at prami.

Ran prami once on a heavy 19-nor stack years back. Never again. The dreams were genuinely disturbing and I caught myself with compulsive buying behaviour at 2am that I didn't clock until after the fact. Caber at 0.25mg twice a week handles my prolactin on NPP at 400mg without any of that. Had it confirmed at week 6 bloods, levels were sitting mid-normal range. Just use caber, test it at the right time, and forget prami exists.

The timing point on prolactin testing is something I got wrong on my first NPP run. Pulled bloods at week 3 thinking I was ahead of it and the number looked fine. Week 8 was a completely different story - prolactin had climbed quietly while I was checking off boxes. Been on 0.25mg caber twice a week as standard protocol since then whenever nandrolone is in the stack.

The symptoms people dismiss are the real early warning. Libido dipping and difficulty finishing are the two that hit first, well before any nipple sensitivity. If both show up together on a 19-nor cycle that is the prolactin signalling you before the labs do. Do not wait for the nipple stuff.

Had one guy in my training group try prami after reading about the potency. One run, one round of bad vivid dreams and the nausea, switched straight back to caber. The consensus from everyone who has actually tried both is the same - caber is the compound, prami is the experiment.

Testing prolactin mid-cycle should be standard practice on any 19-nor stack. The assumption that standard caber dose is handling it without labs to confirm is how problems get missed.