Aromatisation rates across compounds - the pharmacology most people get wrong

2 posts · started by Dutchman · Sep 16, 2024

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Dutchman
Posts: 568
Joined: Apr 2016
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Dutchman
568 posts · joined Apr 2016
#1
The community understanding of aromatisation is often superficial. The actual rate matters enormously for AI dosing and stack planning. Testosterone aromatises at roughly 0.3% of weekly dose per day. Nandrolone aromatises at about 20% of the rate of testosterone. MENT aromatises at roughly 4-5 times the rate of testosterone - this is why Anastrozole is required not optional on MENT. EQ has weak aromatisation but also has anti-estrogenic properties that can crash E2 at high doses even without an AI. Understanding the mechanism tells you how to manage the AI dose. Treating all compounds as equal aromatisers leads to either crashed or uncontrolled E2.
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CaliBro
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Joined: Apr 2018
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CaliBro
283 posts · joined Apr 2018
#2
The MENT aromatisation rate being 4-5x testosterone is the number that catches people off guard. They dose their AI the same way as a high-test cycle and wonder why E2 is still out of control. Each compound needs its own AI calculation based on its actual conversion rate. The EQ anti-estrogenic property crashing E2 at high doses when your normal AI protocol is still running is another one that trips people up. Understanding the mechanism means you anticipate the problem rather than reacting to it.
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