12 weeks test 500 primo 400 - full bloodwork data
13 posts · started by BERLINER · Dec 24, 2025
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SWE LIFTS
164 posts · joined Jul 2018
Aug 22, 2025 at 4:00 PM
#1
The precision of your bloodwork documentation is what this community needs more of. I track all my panels in a spreadsheet going back to baseline. The trend data over multiple cycles is more informative than any single reading. Your LDL trend and HDL suppression numbers match what I see on similar stacks.
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MunichMarc
286 posts · joined Dec 2018
Sep 13, 2025 at 8:00 AM
#2
Really useful bloodwork post. The LDL increase of 18 percent on test and primo is consistent with what I saw on a similar stack. The no-AI outcome is the part that still surprises me each time - you really do not need it at moderate test doses when primo is doing its job.
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AucklandA
130 posts · joined Aug 2019
Sep 16, 2025 at 8:00 AM
#3
Sharing bloodwork openly helps the whole community understand what is actually happening on these compounds. The no-AI result on test and primo is the thing I find most useful - takes one variable out of the equation. Will keep this in mind when planning my next blast.
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Dutchman
587 posts · joined Apr 2016
Oct 24, 2025 at 4:00 PM
#4
The SHBG elevation on primo is an important detail that often gets missed. Methenolone has high SHBG binding affinity which increases total SHBG, reducing free testosterone. At 400mg alongside 500mg test this effect partially offsets the benefit. At higher primo doses or lower test doses the SHBG effect becomes more relevant to how the cycle actually performs.
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CaliBro
300 posts · joined Apr 2018
Nov 13, 2025 at 4:00 PM
#5
Bloodwork at week 12 is exactly when you want it. The no-AI outcome on test and primo matches my experience. E2 self-regulates at moderate test doses when primo is doing its job. The HDL drop is the price you always pay on any cycle - fish oil and clean diet limits the damage but does not eliminate it.
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FrankfurtFit
799 posts · joined Jun 2015
Nov 17, 2025 at 8:00 AM
#6
Your lipid data is precise and well documented. The 18 percent LDL increase at week 12 on test and primo matches the published range for moderate AAS use. The HDL suppression is the primary concern for cumulative cardiovascular risk. I recommend tracking the LDL to HDL ratio over time rather than either marker alone - the ratio is the more predictive metric.
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Paris GH
174 posts · joined Mar 2018
Nov 24, 2025 at 4:00 PM
#7
The no-AI result on test and primo is what I found on a similar stack. E2 at 31 pg/ml without any intervention at week 10. The SHBG mechanism Dutchman describes explains this well. For those of us who find AI management difficult, primo at proper dose removes the problem entirely.
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NYCgains
245 posts · joined Nov 2019
Dec 8, 2025 at 8:00 AM
#8
This kind of data is gold. The no-AI outcome on test and primo is what I experienced too. E2 stayed in range without any aromasin the whole blast. Primo really does have that mild anti-estrogen effect at 400mg. Your lipid numbers are similar to mine as well.
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FLbodybuilder
1,358 posts · joined Feb 2015
Dec 11, 2025 at 8:00 AM
#9
The lipid data at week 12 matches what I see in my own bloodwork on similar stacks. HDL takes the biggest hit on any cycle regardless of compound. Fish oil helps but does not fully offset it. The key is what your numbers look like 12 weeks post cycle - that is the recovery number that matters.
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Beantown Rick
574 posts · joined Jun 2016
Dec 14, 2025 at 8:00 AM
#10
No AI on test and primo is the outcome I get too at that test dose. The E2 stays in range without any intervention. It is one of the most practical benefits of adding primo - you remove the AI variable entirely and simplify the whole blast.
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CapeTown CT
167 posts · joined Oct 2019
Dec 20, 2025 at 8:00 AM
#11
Bloodwork posts like this are gold. The lipid shift is the part that I think is most underappreciated in the community - you do not feel it happening but it is happening on every cycle. Running fish oil, niacin and red yeast rice now alongside the cycle to try and offset the HDL drop.
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BERLINER
531 posts · joined Sep 2016
Dec 24, 2025 at 12:00 AM
#12
Sharing bloodwork from current blast for those who want real data. Week 12, Test E 500mg/wk, Primo 400mg/wk, no AI needed (E2 stayed in range without it - exactly the expected Primo effect). Hematocrit 47.2 percent, well within range. LDL up 18 percent from baseline, HDL down 22 percent. Liver enzymes normal. Total test at roughly 4x baseline. Primo at this dose genuinely kept the cycle dry. No AI is the main practical benefit versus a pure test blast.
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OsloFit
54 posts · joined May 2022
Jan 24, 2026 at 4:00 PM
#13
Bloodwork posts with actual numbers are the most useful thing on this forum for someone like me who is still in the research phase. Seeing what a real 12 week blast looks like on paper - lipid changes, no AI needed on primo, hematocrit - gives me a much clearer picture than any generic compound description.